Prospective evaluation of visual outcomes with three presbyopia-correcting intraocular lenses following cataract surgery

PURPOSE To compare the visual acuity and quality of vision achieved with three widely-used intraocular lenses (IOLs) in subjects with bilateral cataracts. PATIENTS AND METHODS This three-arm, parallel, prospective, partially masked, single-surgeon study randomized 78 subjects to receive bilateral Crystalens® Advanced Optics (AO) accommodating IOLs, AcrySof® IQ ReSTOR® +3.0 multifocal IOLs, or TECNIS® Multifocal IOLs. Examinations were assessed through days 120 to 180. RESULTS The Crystalens AO group had statistically significantly better monocular and binocular, high-contrast (HC) and low-contrast (LC) uncorrected intermediate visual acuity, HC and LC distance-corrected intermediate visual acuity, and significantly fewer monocular and binocular halos and starbursts than did the ReSTOR and TECNIS groups. Monocular and binocular, HC and LC uncorrected near visual acuity exhibited no significant differences among the three lenses. For monocular and binocular HC distance-corrected near visual acuity, the Crystalens AO performed significantly better than the TECNIS and was not significantly different from the ReSTOR. For monocular and binocular LC distance-corrected near visual acuity, the Crystalens AO performed significantly better than both the ReSTOR and the TECNIS. Contrast sensitivity was clinically similar between groups. The Crystalens AO produced statistically fewer halos and starbursts. CONCLUSION All three IOLs had excellent uncorrected acuity results at all distances and had good safety, confirming the established safety and effectiveness of these IOLs. Distance and near vision were similar between all three IOLs, and the Crystalens AO provided statistically significantly better intermediate vision.